Your Diagnosis is Probably* Right
The asterisk that changes everything: Why symptom-based diagnosis in neurodegenerative disease leaves too much room for doubt.
When 'Probable'
Becomes Personal
Every "probable" diagnosis starts a clock—one that keeps ticking while patients and families wait for answers. In neurodegenerative disease, probability isn't just a word—it's a burden carried by patients, families, and physicians alike.
- The average patient receives 2-3 different diagnoses before their journey ends
- Families spend years adjusting to changing prognoses
- Critical time is lost while waiting for symptom progression
- Treatment plans require constant revision as symptoms evolve
What Symptoms Can't Tell You
What you see isn't always what you get. The challenge isn't just about uncertain diagnoses—it's about the complex reality of neurodegenerative disease that symptoms alone can't reveal.
30-50%
Clinically diagnosed Alzheimer's patients who have Lewy body pathology at autopsy
70%
Parkinson's and LBD patients who have mixed pathologies
50%
Cognitive disorder patients with mixed pathologies at autopsy
30%
Clinically diagnosed Parkinson's and DLB patients that do not have Lewy body pathology at autopsy
When diagnosis is based on presuming, every medical decision carries that same uncertainty forward.
- Risk of contraindicated medications being prescribed
- Higher rates of hospitalization from incorrect treatment
- Missed opportunity to prescribe drugs that will improve quality of life
- Inefficient use of healthcare resources
We are the next step in a technological breakthrough that allows us to see a whole family of diseases that couldn't be approached before. And that approach will allow us to have significant impact and to develop tools, drugs, other diagnostics to change these diseases and improve the lives of many people
Get in the Know
Bring biological certainty to your diagnosis with Amprion's SAAmplify-ɑSYN test. Order your shipping kits today and help move your patient beyond a probable diagnosis.
