A Growing Body
of Evidence
Browse the expanding collection of published research featuring our seed amplification assay (SAA) technology.
Scientific Paper
Alzheimer's & Dementia
Self- and study partner–reported cognitive decline in older adults without dementia: The role of α-synuclein and amyloid biomarkers in the Alzheimer’s Disease Neuroimaging Initiative
September 23, 2024
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Brain Communications
LRRK2-associated parkinsonism with and without in vivo evidence of alpha-synuclein aggregates: longitudinal clinical and biomarker characterization
March 6, 2025
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Molecular Neurodegeneration
Alpha synuclein co-pathology is associated with accelerated amyloid-driven tau accumulation in Alzheimer’s disease
March 18, 2025
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Neurology
α-Synuclein Seed Amplification Assay Amplification Parameters and the Risk of Progression in Prodromal Parkinson Disease
March 11, 2025
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Neurobiology of Aging
CSF α-synuclein aggregation is associated with APOE ε4 and progressive cognitive decline in Alzheimer’s disease
February 27, 2025
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Alzheimer's & Dementia
Influence of alpha-synuclein on glucose metabolism in Alzheimer’s disease continuum: Analyses of α-synuclein seed amplification assay and FDG-PET
February 12, 2025
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eBioMedicine
Evidence for alpha-synuclein aggregation in older individuals with hyposmia: a cross-sectional study
February 1, 2025
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Annals of Neurology
Staged Screening Identifies People with Biomarkers Related to Neuronal Alpha-Synuclein Disease
December 24, 2024
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Movement Disorders
Association between the Amplification Parameters of the α-Synuclein Seed Amplification Assay and Clinical and Genetic Subtypes of Parkinson’s Disease
December 18, 2024
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Alzheimer's & Dementia
Contribution of alpha-synuclein pathology to cerebral glucose metabolism in patients with amnestic MCI
August 23, 2024
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The Lancet Neurology
A biological classification of Parkinson’s disease: the SynNeurGe research diagnostic criteria
February 1, 2024
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The Lancet Neurology
A biological definition of neuronal α-synuclein disease: towards an integrated staging system for research
February 1, 2024
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Alzheimer's & Dementia
A cross-sectional study of α-synuclein seed amplification assay in Alzheimer’s disease neuroimaging initiative: Prevalence and associations with Alzheimer’s disease biomarkers and cognitive function
May 21, 2024
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Movement Disorders
Accurate Detection of α-Synuclein Seeds in Cerebrospinal Fluid from Isolated Rapid Eye Movement Sleep Behavior Disorder and Patients with Parkinson’s Disease in the DeNovo Parkinson (DeNoPa) Cohort
February 13, 2024
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Annals of Neurology
Alpha-Synuclein Oligomers and Neurofilament Light Chain Predict Phenoconversion of Pure Autonomic Failure
April 30, 2021
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Get in the Know
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