A Growing Body
of Evidence
Browse the expanding collection of published research featuring our seed amplification assay (SAA) technology.

Scientific Paper
npj Parkinson's Disease
Skin α-synuclein seed amplification assay for the identification of multiple system atrophy

September 8, 2026
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Journal of Parkinson's Disease
Regulatory endorsement for the application of α-synuclein seed amplification assay as a susceptibility and risk biomarker for clinical trials targeting synucleinopathies

September 16, 2026
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Neurology
Alpha-Synuclein Seed Amplification Assay in CSF, Skin, and Submandibular Gland From Incidental Lewy Body Disease and Parkinson Disease

July 28, 2026
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Journal of Neuropathology & Experimental Neurology
Multisite study: Predicting Lewy body disease using skin biopsy α-synuclein seed amplification assays

September 1, 2026
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npj Parkinson's Disease
Clinical correlates of a negative cerebrospinal fluid α-synuclein seed amplification assay result in Parkinson’s disease

April 14, 2026
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Movement Disorders
Rethinking Mitochondrial Parkinson's Disease in the α-Synuclein Seed Amplification Assays Era

May 3, 2026
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Journal of Parkinson's Disease
Collaborative action for biomarker breakthroughs: Validating α-synuclein seed amplification assays in Parkinson's disease

March 19, 2026
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Alzheimer's & Dementia
Prevalence of Lewy body pathology and phenotypic associations in patients with mild cognitive impairment: Evidence from the Interceptor study

June 15, 2026
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Alzheimer's & Dementia
Atrophy signature for alpha-synuclein copathology in Alzheimer's disease

May 24, 2026
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Neurobioogy of Disease
Combination of CSF α-synuclein seed amplification assay and amyloid-β42 predicts cognitive decline in Parkinson's disease

May 16, 2026
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Alzheimer's & Dementia
Effects of α-synuclein pathology on synaptic dysfunction and clinical outcomes in normal aging

May 3, 2026
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Alzheimer's & Dementia
Alpha-synuclein co-pathology in a real-world early Alzheimer's disease cohort

March 24, 2026
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Journal of Parkinson's Disease
Faster reaction times of CSF alpha-synuclein seed amplification assay predict the diffuse malignant subtype of Parkinson's disease at 10-year follow-up

January 29, 2026
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Journal of Parkinson's Disease
Analysis of α-synuclein seed amplification assay in carriers of GBA1 and LRRK2 pathogenic variants

January 23, 2026
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Neurobiology of Disease
Cerebrospinal fluid α-synuclein seed amplification assay positivity is associated with increased plasma neurofilament light chain in Alzheimer's disease

January 1, 2026
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