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Lab technician running an alpha-synuclein seed amplification assay (𝛼-SYN-saa) to look for misfolded alpha synuclein proteins.

Amprion is at AD/PD 2026, booth 60

Copenhagen, DK | March 17-21, 2026

Tackle challenging diagnoses with the power of biology.

AD/PD 2026 Poster 696


DESIGN OF EXPERIMENT–DRIVEN OPTIMIZATION AND VALIDATION OF A SEED AMPLIFICATION ASSAY FOR α-SYNUCLEIN DETECTION IN PERIPHERAL FLUIDS.

AD/PD 2026 Poster 1473

DIFFERENTIATION OF TYPE 1 AND TYPE 2 ALPHA-SYNUCLEIN SEEDS IN SKIN BIOPSY SAMPLES USING SEED AMPLIFICATION ASSAY.

Scientific Paper

Journal of Parkinson's Disease
Faster reaction times of CSF alpha-synuclein seed amplification assay predict the diffuse malignant subtype of Parkinson's disease at 10-year follow-up
January 29, 2026
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Scientific Paper

Journal of Parkinson's disease
Analysis of α-synuclein seed amplification assay in carriers of GBA1 and LRRK2 pathogenic variants
January 23, 2026
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Scientific Paper

Neurobiology of disease
Cerebrospinal fluid α-synuclein seed amplification assay positivity is associated with increased plasma neurofilament light chain in Alzheimer's disease
January 1, 2026
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Scientific Paper

Molecular psychiatry
In vivo-measured Lewy body pathology is associated with neuropsychiatric symptoms across the Alzheimer's disease continuum
December 14, 2025
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Scientific Paper

Movement disorders
Skin Biopsy for Phosphorylated α-Synuclein in Mild Cognitive Impairment or Dementia Due to Lewy Body Disease in a Convenience Cohort from a Subspecialty Behavioral Neurology Practice
December 9, 2025
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Scientific Paper

Journal of Neurology
Longitudinal decline in striatal DAT binding in LRRK2 Parkinson's disease: connections with CSF α-synuclein seeding activity
September 13, 2025
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Scientific Paper

Neurology
α-Synuclein Seed Amplifications Assay in a Cohort With Cognitive Impairment Performance and Interactions With CSF and Plasma Biomarkers
October 7, 2025
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Scientific Paper

Movement Disorders Clinical Practice
Prodromal Lewy Body Symptoms and α-Synuclein Seeding in Idiopathic Olfactory Dysfunction
September 8, 2025
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Scientific Paper

Annals of Neurology
Cognitive Performance in Early Neuronal Synuclein Disease with Hyposmia but without Motor Disability: Association with Dopamine Deficiency and Isolated Rapid Eye Movement Sleep Behavior Disorder
July 11, 2025
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Scientific Paper

Movement Disorders
Comparison of Two α-Synuclein Seed Amplification Assays for Discrimination of Parkinson Disease and Atypical Parkinsonism
August 20, 2025
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Scientific Paper

npj Parkinson's Disease
Phosphorylated α-synuclein in CSF and plasma does not reflect synucleinopathy
August 7, 2025
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Scientific Paper

Nature Communications
Two-step detection of Lewy body pathology via smell-function testing and CSF α-synuclein seed amplification
August 5, 2025
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Scientific Paper

The Lancet Neurology
Diagnostic and prognostic value of α-synuclein seed amplification assay kinetic measures in Parkinson's disease: a longitudinal cohort study
July 1, 2025
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Scientific Paper

The Lancet Neurology
Unlocking the full clinical potential of the α-synuclein seed amplification assay
July 1, 2025
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Get in the Know

Bring biological certainty to your diagnosis with Amprion's SAAmplify-ɑSYN test. Order your  shipping kits today and help move your patient beyond a probable diagnosis.