A Growing Body
of Evidence
Browse the expanding collection of published research featuring our seed amplification assay (SAA) technology.
Scientific Paper
Annals of Clinical and Translational Neurology
Alpha-synuclein RT-QuIC in the CSF of patients with alpha-synucleinopathies
August 28, 2016
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International Journal of Molecular Sciences
Analysis of Protein Conformational Strains-A Key for New Diagnostic Methods of Human Diseases
April 17, 2020
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The Lancet Neurology
Assessment of heterogeneity among participants in the Parkinson’s Progression Markers Initiative cohort using α-synuclein seed amplification: a cross-sectional study
May 1, 2023
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Neurology
Association of CSF α-Synuclein Seeding Amplification Assay Results With Clinical Features of Possible and Probable Dementia With Lewy Bodies
July 16, 2024
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Alzheimer's & Dementia
Associations between misfolded alpha-synuclein aggregates and Alzheimer’s disease pathology in vivo
September 11, 2024
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Alzheimer's & Dementia
Clinicopathological correlation of cerebrospinal fluid alpha-synuclein seed amplification assay in a behavioral neurology autopsy cohort
March 27, 2024
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Neurology
CSF α-Synuclein Seed Amplification Assay in Patients With Atypical Parkinsonian Disorders
September 29, 2024
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The Lancet Neurology
Detection of α-synuclein in CSF by RT-QuIC in patients with isolated rapid-eye-movement sleep behaviour disorder: a longitudinal observational study
March 1, 2021
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Nature
Discriminating α-synuclein strains in Parkinson’s disease and multiple system atrophy
February 5, 2020
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Movement Disorders
Evaluation of Cerebrospinal Fluid α-Synuclein Seed Amplification Assay in Progressive Supranuclear Palsy and Corticobasal Syndrome
November 20, 2024
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Acta Neuropathologica Communications
High diagnostic performance of independent alpha-synuclein seed amplification assays for detection of early Parkinson’s disease
November 26, 2021
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Alzheimer's & Dementia
Investigating alpha-synuclein co-pathology in Alzheimer’s disease by means of cerebrospinal fluid alpha-synuclein seed amplification assay
February 7, 2024
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European Journal of Neurology
Misfolded alpha-synuclein in amyotrophic lateral sclerosis: Implications for diagnosis and treatment
January 25, 2024
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Annals of Clinical and Translational Neurology
Multiple biomarkers improve diagnostic accuracy across Lewy body and Alzheimer’s disease spectra
March 4, 2024
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Acta Neuropathologica Communications
Rapid and ultra-sensitive quantitation of disease-associated α-synuclein seeds in brain and cerebrospinal fluid by αSyn RT-QuIC
February 19, 0218
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Get in the Know
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