A Growing Body
of Evidence

Browse the expanding collection of published research featuring our seed amplification assay (SAA) technology.

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Acta Neuropathologica Communications
Acta Neuropathologica Communications
Acta Neuropathologica Communications
Acta Neuropathologica Communications
Alzheimer's & Dementia
Alzheimer's & Dementia
Alzheimer's & Dementia
Alzheimer's & Dementia
Alzheimer's & Dementia
Alzheimer's & Dementia
Alzheimer's & Dementia
Alzheimer's & Dementia
Alzheimer's & Dementia
Alzheimer's & Dementia
Annals of Clinical and Translational Neurology
Annals of Clinical and Translational Neurology
Annals of Neurology
Annals of Neurology
Annals of Neurology
Annals of Neurology
Brain
Brain Communications
European Journal of Neurology
International Journal of Molecular Sciences
Journal of Movement Disorders
Journal of Neurology
Journal of Neurology
Molecular Neurodegeneration
Movement Disorders
Movement Disorders
Movement Disorders
Movement Disorders
Movement Disorders
Movement Disorders Clinical Practice
Nature
Nature
Nature Communications
Neurobiology of Aging
Neurology
Neurology
Neurology
Neurology
The Lancet Neurology
The Lancet Neurology
The Lancet Neurology
The Lancet Neurology
The Lancet Neurology
The Lancet Neurology
The Lancet Neurology
Trends in Biotechnology
eBioMedicine
eBioMedicine
npj Parkinson's Disease
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Scientific Paper

Neurology
α-Synuclein Seed Amplification Assay Amplification Parameters and the Risk of Progression in Prodromal Parkinson Disease
March 11, 2025
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Scientific Paper

Neurobiology of Aging
CSF α-synuclein aggregation is associated with APOE ε4 and progressive cognitive decline in Alzheimer’s disease
February 27, 2025
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Scientific Paper

Alzheimer's & Dementia
Influence of alpha-synuclein on glucose metabolism in Alzheimer’s disease continuum: Analyses of α-synuclein seed amplification assay and FDG-PET
February 12, 2025
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Scientific Paper

eBioMedicine
Evidence for alpha-synuclein aggregation in older individuals with hyposmia: a cross-sectional study
February 1, 2025
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Scientific Paper

Annals of Neurology
Staged Screening Identifies People with Biomarkers Related to Neuronal Alpha-Synuclein Disease
December 24, 2024
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Scientific Paper

Movement Disorders
Association between the Amplification Parameters of the α-Synuclein Seed Amplification Assay and Clinical and Genetic Subtypes of Parkinson’s Disease
December 18, 2024
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Scientific Paper

Alzheimer's & Dementia
Contribution of alpha-synuclein pathology to cerebral glucose metabolism in patients with amnestic MCI
August 23, 2024
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Literature Review

The Lancet Neurology
A biological classification of Parkinson’s disease: the SynNeurGe research diagnostic criteria
February 1, 2024
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Literature Review

The Lancet Neurology
A biological definition of neuronal α-synuclein disease: towards an integrated staging system for research
February 1, 2024
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Scientific Paper

Alzheimer's & Dementia
A cross-sectional study of α-synuclein seed amplification assay in Alzheimer’s disease neuroimaging initiative: Prevalence and associations with Alzheimer’s disease biomarkers and cognitive function
May 21, 2024
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Scientific Paper

Movement Disorders
Accurate Detection of α-Synuclein Seeds in Cerebrospinal Fluid from Isolated Rapid Eye Movement Sleep Behavior Disorder and Patients with Parkinson’s Disease in the DeNovo Parkinson (DeNoPa) Cohort
February 13, 2024
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Scientific Paper

Annals of Neurology
Alpha-Synuclein Oligomers and Neurofilament Light Chain Predict Phenoconversion of Pure Autonomic Failure
April 30, 2021
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Scientific Paper

Annals of Clinical and Translational Neurology
Alpha-synuclein RT-QuIC in the CSF of patients with alpha-synucleinopathies
August 28, 2016
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Scientific Paper

International Journal of Molecular Sciences
Analysis of Protein Conformational Strains-A Key for New Diagnostic Methods of Human Diseases
April 17, 2020
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Scientific Paper

The Lancet Neurology
Assessment of heterogeneity among participants in the Parkinson’s Progression Markers Initiative cohort using α-synuclein seed amplification: a cross-sectional study
May 1, 2023
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Bring biological certainty to your diagnosis with Amprion's SAAmplify-ɑSYN test. Order your shipping kits today and help move your patient beyond a probable diagnosis.