A Growing Body
of Evidence
Browse the expanding collection of published research featuring our seed amplification assay (SAA) technology.
Scientific Paper
Journal of Neurology
Longitudinal decline in striatal DAT binding in LRRK2 Parkinson's disease: connections with CSF α-synuclein seeding activity
September 13, 2025
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Neurology
α-Synuclein Seed Amplifications Assay in a Cohort With Cognitive Impairment Performance and Interactions With CSF and Plasma Biomarkers
October 7, 2025
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Alzheimer's & Dementia
Self- and study partner–reported cognitive decline in older adults without dementia: The role of α-synuclein and amyloid biomarkers in the Alzheimer’s Disease Neuroimaging Initiative
September 23, 2024
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Brain Communications
LRRK2-associated parkinsonism with and without in vivo evidence of alpha-synuclein aggregates: longitudinal clinical and biomarker characterization
March 6, 2025
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Molecular Neurodegeneration
Alpha synuclein co-pathology is associated with accelerated amyloid-driven tau accumulation in Alzheimer’s disease
March 18, 2025
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Neurology
α-Synuclein Seed Amplification Assay Amplification Parameters and the Risk of Progression in Prodromal Parkinson Disease
March 11, 2025
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Neurobiology of Aging
CSF α-synuclein aggregation is associated with APOE ε4 and progressive cognitive decline in Alzheimer’s disease
February 27, 2025
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Alzheimer's & Dementia
Influence of alpha-synuclein on glucose metabolism in Alzheimer’s disease continuum: Analyses of α-synuclein seed amplification assay and FDG-PET
February 12, 2025
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eBioMedicine
Evidence for alpha-synuclein aggregation in older individuals with hyposmia: a cross-sectional study
February 1, 2025
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Annals of Neurology
Staged Screening Identifies People with Biomarkers Related to Neuronal Alpha-Synuclein Disease
December 24, 2024
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Movement Disorders
Association between the Amplification Parameters of the α-Synuclein Seed Amplification Assay and Clinical and Genetic Subtypes of Parkinson’s Disease
December 18, 2024
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Alzheimer's & Dementia
Contribution of alpha-synuclein pathology to cerebral glucose metabolism in patients with amnestic MCI
August 23, 2024
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The Lancet Neurology
A biological classification of Parkinson’s disease: the SynNeurGe research diagnostic criteria
February 1, 2024
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The Lancet Neurology
A biological definition of neuronal α-synuclein disease: towards an integrated staging system for research
February 1, 2024
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Alzheimer's & Dementia
A cross-sectional study of α-synuclein seed amplification assay in Alzheimer’s disease neuroimaging initiative: Prevalence and associations with Alzheimer’s disease biomarkers and cognitive function
May 21, 2024
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Get in the Know
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