A Growing Body
of Evidence
Browse the expanding collection of published research featuring our seed amplification assay (SAA) technology.
Scientific Paper
npj Parkinson's Disease
Phosphorylated α-synuclein in CSF and plasma does not reflect synucleinopathy
August 7, 2025
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Movement Disorders
Comparison of Two α-Synuclein Seed Amplification Assays for Discrimination of Parkinson Disease and Atypical Parkinsonism
August 20, 2025
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Annals of Neurology
Cognitive Performance in Early Neuronal Synuclein Disease with Hyposmia but without Motor Disability: Association with Dopamine Deficiency and Isolated Rapid Eye Movement Sleep Behavior Disorder
July 11, 2025
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eBioMedicine
Baseline α-synuclein seeding activity and disease progression in sporadic and genetic Parkinson's disease in the PPMI cohort
September 1, 2025
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Movement Disorders Clinical Practice
Prodromal Lewy Body Symptoms and α-Synuclein Seeding in Idiopathic Olfactory Dysfunction
September 8, 2025
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Journal of Neurology
Longitudinal decline in striatal DAT binding in LRRK2 Parkinson's disease: connections with CSF α-synuclein seeding activity
September 13, 2025
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Neurology
α-Synuclein Seed Amplifications Assay in a Cohort With Cognitive Impairment Performance and Interactions With CSF and Plasma Biomarkers
October 7, 2025
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Alzheimer's & Dementia
Self- and study partner–reported cognitive decline in older adults without dementia: The role of α-synuclein and amyloid biomarkers in the Alzheimer’s Disease Neuroimaging Initiative
September 23, 2024
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Brain Communications
LRRK2-associated parkinsonism with and without in vivo evidence of alpha-synuclein aggregates: longitudinal clinical and biomarker characterization
March 6, 2025
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Molecular Neurodegeneration
Alpha synuclein co-pathology is associated with accelerated amyloid-driven tau accumulation in Alzheimer’s disease
March 18, 2025
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Neurology
α-Synuclein Seed Amplification Assay Amplification Parameters and the Risk of Progression in Prodromal Parkinson Disease
March 11, 2025
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Neurobiology of Aging
CSF α-synuclein aggregation is associated with APOE ε4 and progressive cognitive decline in Alzheimer’s disease
February 27, 2025
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Alzheimer's & Dementia
Influence of alpha-synuclein on glucose metabolism in Alzheimer’s disease continuum: Analyses of α-synuclein seed amplification assay and FDG-PET
February 12, 2025
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eBioMedicine
Evidence for alpha-synuclein aggregation in older individuals with hyposmia: a cross-sectional study
February 1, 2025
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Annals of Neurology
Staged Screening Identifies People with Biomarkers Related to Neuronal Alpha-Synuclein Disease
December 24, 2024
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Get in the Know
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