A Growing Body
of Evidence
Browse the expanding collection of published research featuring our seed amplification assay (SAA) technology.

Scientific Paper
Movement Disorders
Association between the Amplification Parameters of the α-Synuclein Seed Amplification Assay and Clinical and Genetic Subtypes of Parkinson’s Disease

December 18, 2024
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Alzheimer's & Dementia
Contribution of alpha-synuclein pathology to cerebral glucose metabolism in patients with amnestic MCI

August 23, 2024
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The Lancet Neurology
A biological classification of Parkinson’s disease: the SynNeurGe research diagnostic criteria

February 1, 2024
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The Lancet Neurology
A biological definition of neuronal α-synuclein disease: towards an integrated staging system for research

February 1, 2024
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Alzheimer's & Dementia
A cross-sectional study of α-synuclein seed amplification assay in Alzheimer’s disease neuroimaging initiative: Prevalence and associations with Alzheimer’s disease biomarkers and cognitive function

May 21, 2024
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Movement Disorders
Accurate Detection of α-Synuclein Seeds in Cerebrospinal Fluid from Isolated Rapid Eye Movement Sleep Behavior Disorder and Patients with Parkinson’s Disease in the DeNovo Parkinson (DeNoPa) Cohort

February 13, 2024
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Annals of Neurology
Alpha-Synuclein Oligomers and Neurofilament Light Chain Predict Phenoconversion of Pure Autonomic Failure

April 30, 2021
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Annals of Clinical and Translational Neurology
Alpha-synuclein RT-QuIC in the CSF of patients with alpha-synucleinopathies

August 28, 2016
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International Journal of Molecular Sciences
Analysis of Protein Conformational Strains-A Key for New Diagnostic Methods of Human Diseases

April 17, 2020
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The Lancet Neurology
Assessment of heterogeneity among participants in the Parkinson’s Progression Markers Initiative cohort using α-synuclein seed amplification: a cross-sectional study

May 1, 2023
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Neurology
Association of CSF α-Synuclein Seeding Amplification Assay Results With Clinical Features of Possible and Probable Dementia With Lewy Bodies

July 16, 2024
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Alzheimer's & Dementia
Associations between misfolded alpha-synuclein aggregates and Alzheimer’s disease pathology in vivo

September 11, 2024
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Alzheimer's & Dementia
Clinicopathological correlation of cerebrospinal fluid alpha-synuclein seed amplification assay in a behavioral neurology autopsy cohort

March 27, 2024
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Neurology
CSF α-Synuclein Seed Amplification Assay in Patients With Atypical Parkinsonian Disorders

September 29, 2024
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The Lancet Neurology
Detection of α-synuclein in CSF by RT-QuIC in patients with isolated rapid-eye-movement sleep behaviour disorder: a longitudinal observational study

March 1, 2021
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