A Growing Body
of Evidence

Browse the expanding collection of published research featuring our seed amplification assay (SAA) technology.

Thank you! Your submission has been received!

Oops! Something went wrong while submitting the form.

Position Paper

Alzheimer's & Dementia

Revised criteria for diagnosis and staging of Alzheimer’s disease: Alzheimer’s Association Workgroup

June 27, 2024

Scientific Paper

Journal of Neurology

Seed amplification assay results illustrate discrepancy in Parkinson’s disease clinical diagnostic accuracy and error rates

September 17, 2023

Scientific Paper

Acta Neuropathologica Communications

Streamlined alpha-synuclein RT-QuIC assay for various biospecimens in Parkinson’s disease and dementia with Lewy bodies

April 7, 2021

Scientific Paper

Nature

Structures of α-synuclein filaments from human brains with Lewy pathology

September 15, 2022

Scientific Paper

Acta Neuropathologica Communications

Ultrasensitive RT-QuIC assay with high sensitivity and specificity for Lewy body-associated synucleinopathies

April 27, 2024

Scientific Paper

Alzheimer's & Dementia

α-Synuclein seed amplification assay detects Lewy body co-pathology in autosomal dominant Alzheimer’s disease late in the disease course and dependent on Lewy pathology burden

Position Paper

Movement Disorders

α-Synuclein seed amplification assay shows potential to unmask pathology and enable biologically-based therapeutic development

June 1, 2023

Scientific Paper

Annals of Neurology

α-Synuclein Seed Amplification in CSF and Brain from Patients with Different Brain Distributions of Pathological α-Synuclein in the Context of Co-Pathology and Non-LBD Diagnoses

July 29, 2024

Literature Review

Trends in Biotechnology

α-Synuclein seed amplification technology for Parkinson’s disease and related synucleinopathies

July 1, 2024

Scientific Paper

Alzheimer's & Dementia

Association of CSF α-synuclein seed amplification assay positivity with disease progression and cognitive decline: A longitudinal Alzheimer’s Disease Neuroimaging Initiative study

October 20, 2024

Scientific Paper

The Lancet Neurology

Sensitivity and specificity of a seed amplification assay for diagnosis of multiple system atrophy: a multicentre cohort study

November 21, 2024

Get in the Know

Bring biological certainty to your diagnosis with Amprion's SAAmplify-ɑSYN test. Order your shipping kits today and help move your patient beyond a probable diagnosis.