A Growing Body
of Evidence

Browse the expanding collection of published research featuring our seed amplification assay (SAA) technology.

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Scientific Paper

Nature

Structures of α-synuclein filaments from human brains with Lewy pathology

September 15, 2022

Scientific Paper

Acta Neuropathologica Communications

Ultrasensitive RT-QuIC assay with high sensitivity and specificity for Lewy body-associated synucleinopathies

April 27, 2024

Scientific Paper

Alzheimer's & Dementia

α-Synuclein seed amplification assay detects Lewy body co-pathology in autosomal dominant Alzheimer’s disease late in the disease course and dependent on Lewy pathology burden

Position Paper

Movement Disorders

α-Synuclein seed amplification assay shows potential to unmask pathology and enable biologically-based therapeutic development

June 1, 2023

Scientific Paper

Annals of Neurology

α-Synuclein Seed Amplification in CSF and Brain from Patients with Different Brain Distributions of Pathological α-Synuclein in the Context of Co-Pathology and Non-LBD Diagnoses

July 29, 2024

Literature Review

Trends in Biotechnology

α-Synuclein seed amplification technology for Parkinson’s disease and related synucleinopathies

July 1, 2024

Scientific Paper

Alzheimer's & Dementia

Association of CSF α-synuclein seed amplification assay positivity with disease progression and cognitive decline: A longitudinal Alzheimer’s Disease Neuroimaging Initiative study

October 20, 2024

Scientific Paper

The Lancet Neurology

Sensitivity and specificity of a seed amplification assay for diagnosis of multiple system atrophy: a multicentre cohort study

November 21, 2024

Get in the Know

Bring biological certainty to your diagnosis with Amprion's SAAmplify-ɑSYN test. Order your shipping kits today and help move your patient beyond a probable diagnosis.